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SELECT 
  1 
FROM 
  cscart_lock_keys 
WHERE 
  key_id = 'c0166095dbd289e4920b35c3000a3f1b676377136f98b6e9cc81eb79d00a59aa' 
  AND token = 'wIC/SIA4YnS5gu4vMeBna3n6MTWaNmXRkUofImC0pvQ=' 
  AND expiry_at > UNIX_TIMESTAMP(NOW())

Query time 0.00033

JSON explain

{
  "query_block": {
    "select_id": 1,
    "message": "no matching row in const table"
  }
}