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SELECT 
  1 
FROM 
  cscart_lock_keys 
WHERE 
  key_id = 'b7e5d8b6f3b669ab59f6e535b73a8da1d6354be22e156638551c2b9d9daf6a6d' 
  AND token = 'nYNCdMQD+CCK/PuLemUvRx2u5ucVfHDaHp82PVm/38c=' 
  AND expiry_at > UNIX_TIMESTAMP(NOW())

Query time 0.00024

JSON explain

{
  "query_block": {
    "select_id": 1,
    "message": "no matching row in const table"
  }
}