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SELECT 
  1 
FROM 
  cscart_lock_keys 
WHERE 
  key_id = '025248bc9d4e1386bb542f8626c18639f30468b73ef721022c51d895ff280de1' 
  AND token = 'n3yyyvl1jm7IAWmmdUCRjhyi4aENprRbKy8vtkzo2P0=' 
  AND expiry_at > UNIX_TIMESTAMP(NOW())

Query time 0.00025

JSON explain

{
  "query_block": {
    "select_id": 1,
    "message": "no matching row in const table"
  }
}