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SELECT 
  1 
FROM 
  cscart_lock_keys 
WHERE 
  key_id = 'a41ded5699e4c59bbd06c851753de12bff192dd13518601e1e8e3c97abdf4910' 
  AND token = '+xnD2UZk/HEatl0vxCLUWHiq/ea1VxD0TtNnBgbY2G4=' 
  AND expiry_at > UNIX_TIMESTAMP(NOW())

Query time 0.00039

JSON explain

{
  "query_block": {
    "select_id": 1,
    "message": "no matching row in const table"
  }
}