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SELECT 
  1 
FROM 
  cscart_lock_keys 
WHERE 
  key_id = 'fdceae0e0280186ae3e0e1489105c99a94b94e5916dc80768985b91421a99f53' 
  AND token = 'PsT4I1WmSAyzD8Z2eNvO3RsBLWHDty/HB33cDM8N+PY=' 
  AND expiry_at > UNIX_TIMESTAMP(NOW())

Query time 0.00025

JSON explain

{
  "query_block": {
    "select_id": 1,
    "message": "no matching row in const table"
  }
}