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SELECT 
  1 
FROM 
  cscart_lock_keys 
WHERE 
  key_id = '2e36f8b2e170d3aafee061d0f16b207f5004584ddd50b0d2d042f9442546ca8d' 
  AND token = 'TzItsgXV7ZMfjCIy+Dcx//BBK+yoYMd0HS1C+H2jG2Q=' 
  AND expiry_at > UNIX_TIMESTAMP(NOW())

Query time 0.00071

JSON explain

{
  "query_block": {
    "select_id": 1,
    "message": "no matching row in const table"
  }
}