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SELECT 
  1 
FROM 
  cscart_lock_keys 
WHERE 
  key_id = '41f4166bae29895c8c27cdeb2b78ce0847950ea3970fbffcf7c7af5494c5c8b8' 
  AND token = 'OphZPzbA/3SELinL9DkwbqfSVa0yRtn+TyVVet/kEdc=' 
  AND expiry_at > UNIX_TIMESTAMP(NOW())

Query time 0.00026

JSON explain

{
  "query_block": {
    "select_id": 1,
    "message": "no matching row in const table"
  }
}