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SELECT 
  1 
FROM 
  cscart_lock_keys 
WHERE 
  key_id = 'c51b3d282ef3219180cc183da35426f57342246f038bd5d45d6d0bfed9a05259' 
  AND token = '4x+kEAaxNwMkR/+xqHC19wlIW8mpG22R/FR4l82IZxo=' 
  AND expiry_at > UNIX_TIMESTAMP(NOW())

Query time 0.00027

JSON explain

{
  "query_block": {
    "select_id": 1,
    "message": "no matching row in const table"
  }
}