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SELECT 
  1 
FROM 
  cscart_lock_keys 
WHERE 
  key_id = '2c5e96876c14b8186f0f31346465c2062e9b1539313d4e0a744b2a03eb0716fb' 
  AND token = '9Ss0Czu8v+WZpzaEoRs6+4F/pZqVTO7NsQlFq0UPb2Y=' 
  AND expiry_at > UNIX_TIMESTAMP(NOW())

Query time 0.00036

JSON explain

{
  "query_block": {
    "select_id": 1,
    "message": "no matching row in const table"
  }
}