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SELECT 
  1 
FROM 
  cscart_lock_keys 
WHERE 
  key_id = 'f2574c3a7db489f3ac754978b8aa8e0b98b8fbcd369838608fd376ade3543057' 
  AND token = 'kFgCWf+DUv6T5c3R2ktBdhGG6rLT3ZVatFPoOtuoEsU=' 
  AND expiry_at > UNIX_TIMESTAMP(NOW())

Query time 0.00042

JSON explain

{
  "query_block": {
    "select_id": 1,
    "message": "no matching row in const table"
  }
}