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SELECT 
  1 
FROM 
  cscart_lock_keys 
WHERE 
  key_id = '4c9274db066af9e15fe9ad8f3ebdbfabed5d04291d0adc9d555e1a40fc79dd6e' 
  AND token = 'Ueyf/SL9iH1dtcp28HUHaVHL1a/j7JnygpmlurHcy5I=' 
  AND expiry_at > UNIX_TIMESTAMP(NOW())

Query time 0.00030

JSON explain

{
  "query_block": {
    "select_id": 1,
    "message": "no matching row in const table"
  }
}