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SELECT 
  1 
FROM 
  cscart_lock_keys 
WHERE 
  key_id = '2e4646d2759bad75e48a13fd73b057e63644e789f49459fbe19abdd657ee8e4c' 
  AND token = 'MygDIeniC/EYL8ZsgtUjGi73kTt7MrnP8Q6L6QmpYbk=' 
  AND expiry_at > UNIX_TIMESTAMP(NOW())

Query time 0.00030

JSON explain

{
  "query_block": {
    "select_id": 1,
    "message": "no matching row in const table"
  }
}