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SELECT 
  1 
FROM 
  cscart_lock_keys 
WHERE 
  key_id = 'c38417785f3fe2e69414998b78b35c31d0ebf746ca13da41a9dbd427df58d787' 
  AND token = 'y+mv30c9tOomqp8XKywbrF+V3ZNEPxNyS+7NZTI9sfk=' 
  AND expiry_at > UNIX_TIMESTAMP(NOW())

Query time 0.00033

JSON explain

{
  "query_block": {
    "select_id": 1,
    "message": "no matching row in const table"
  }
}