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SELECT 
  1 
FROM 
  cscart_lock_keys 
WHERE 
  key_id = '3c427fa8143b99b27eca0f69b30ecc0c087f34026bb6fdb1b51802127096c2d9' 
  AND token = 'KrCJVXd3RAIb/HLqQC3kutVnOrcwp5CCsj7XeVf8nOY=' 
  AND expiry_at > UNIX_TIMESTAMP(NOW())

Query time 0.00033

JSON explain

{
  "query_block": {
    "select_id": 1,
    "message": "no matching row in const table"
  }
}