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SELECT 
  1 
FROM 
  cscart_lock_keys 
WHERE 
  key_id = '8b5f6ac58f1e6fd66c78f685009221175b63dd821ba0bfbd032c182a79554bf4' 
  AND token = 'eVfvr9zWhg0f0+haggNoc6+MfvgM8M/15M/Yj3XnjJI=' 
  AND expiry_at > UNIX_TIMESTAMP(NOW())

Query time 0.00022

JSON explain

{
  "query_block": {
    "select_id": 1,
    "message": "no matching row in const table"
  }
}