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SELECT 
  1 
FROM 
  cscart_lock_keys 
WHERE 
  key_id = 'cf297c7f3cbb8766b01aa1a29d820e3ec893313d4f16edf5348a1f8fa2e966af' 
  AND token = 'T7HTB02y+VxxZsJPItISa96nIMjhMCcCfc2rBqNR6VI=' 
  AND expiry_at > UNIX_TIMESTAMP(NOW())

Query time 0.00020

JSON explain

{
  "query_block": {
    "select_id": 1,
    "message": "no matching row in const table"
  }
}