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SELECT 
  1 
FROM 
  cscart_lock_keys 
WHERE 
  key_id = '805661051a50be62f87e7462d2cae202b4224ae4b987a559b26009051e449ac4' 
  AND token = 'tlBJVtgJyevVkF6rpTQqdsYCspu+8vR8AHCSGU0ZKSM=' 
  AND expiry_at > UNIX_TIMESTAMP(NOW())

Query time 0.00056

JSON explain

{
  "query_block": {
    "select_id": 1,
    "message": "no matching row in const table"
  }
}