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SELECT 
  1 
FROM 
  cscart_lock_keys 
WHERE 
  key_id = '9eb8c76a40484592e99ed1108931afca4e2fb5fdd9dbe79088c9ab51478d755e' 
  AND token = 'IO0hBsS+voXv3ULyrZGQguSKGEfqLo35Q33Bf9GzXuE=' 
  AND expiry_at > UNIX_TIMESTAMP(NOW())

Query time 0.00020

JSON explain

{
  "query_block": {
    "select_id": 1,
    "message": "no matching row in const table"
  }
}