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SELECT 
  1 
FROM 
  cscart_lock_keys 
WHERE 
  key_id = '88febff5c616f4be662fdc307c2dc0fec96559f2e66310e13ed454cfe925e86f' 
  AND token = '4yNH0W3IP+SObiM1xw75mfe2tq38d6gfLYCNwAThvfY=' 
  AND expiry_at > UNIX_TIMESTAMP(NOW())

Query time 0.00042

JSON explain

{
  "query_block": {
    "select_id": 1,
    "message": "no matching row in const table"
  }
}