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SELECT 
  1 
FROM 
  cscart_lock_keys 
WHERE 
  key_id = '80d8ab7c217bd92f6406fcaa6ea3585ea7710b0fb5c1d50dbc2bbce60ef1c979' 
  AND token = 'E90EBhUMBmWwui6GsBraDBdo0AwxmTN8R3hQQEgK6MI=' 
  AND expiry_at > UNIX_TIMESTAMP(NOW())

Query time 0.00055

JSON explain

{
  "query_block": {
    "select_id": 1,
    "message": "no matching row in const table"
  }
}