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SELECT 
  1 
FROM 
  cscart_lock_keys 
WHERE 
  key_id = '75af578d278ade15358872fec72a5fc792be2de8f14f497148be152b6f481944' 
  AND token = 'ktDzCsJJztS3VCTh6cf5dKY2SfHXVJ3fcCC7cwh0uPU=' 
  AND expiry_at > UNIX_TIMESTAMP(NOW())

Query time 0.00024

JSON explain

{
  "query_block": {
    "select_id": 1,
    "message": "no matching row in const table"
  }
}