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SELECT 
  1 
FROM 
  cscart_lock_keys 
WHERE 
  key_id = '6312f2e5c2e497f041098911dbc48b7609545ee9dd6f6f3ede63e08a608b4d58' 
  AND token = '12aVBPB1vptfOPwqtzwDbylOAJpHtIICkR0GXSy72qc=' 
  AND expiry_at > UNIX_TIMESTAMP(NOW())

Query time 0.00025

JSON explain

{
  "query_block": {
    "select_id": 1,
    "message": "no matching row in const table"
  }
}