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SELECT 
  1 
FROM 
  cscart_lock_keys 
WHERE 
  key_id = 'e1e300bc97206ecae7f74dc7fa19a37eeb19dbc6beba31505a4ddc1d19131a56' 
  AND token = '2ovjhbaOuEPtTIC0nCovrdR7AuaTq5sQ3v4KZT6Pc/0=' 
  AND expiry_at > UNIX_TIMESTAMP(NOW())

Query time 0.00035

JSON explain

{
  "query_block": {
    "select_id": 1,
    "message": "no matching row in const table"
  }
}