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SELECT 
  1 
FROM 
  cscart_lock_keys 
WHERE 
  key_id = '59eba7df994777a918f25ac7d248a7ef19fb34b5e7f0016486c34503705c3384' 
  AND token = '7afkz0qhpHs+OV550yPqdO9lKRgKAWmNmNiDbSmZRHs=' 
  AND expiry_at > UNIX_TIMESTAMP(NOW())

Query time 0.00035

JSON explain

{
  "query_block": {
    "select_id": 1,
    "message": "no matching row in const table"
  }
}