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SELECT 
  1 
FROM 
  cscart_lock_keys 
WHERE 
  key_id = '95a926194929cb1c84bcaba3d4050ab45ea8c7cb9ec2b4e7a68ce07564f849bf' 
  AND token = 'R9tS0RE9GwDdNVmC0IBGXq8tLVGS73TMNxY8wS1a7v0=' 
  AND expiry_at > UNIX_TIMESTAMP(NOW())

Query time 0.00021

JSON explain

{
  "query_block": {
    "select_id": 1,
    "message": "no matching row in const table"
  }
}