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SELECT 
  1 
FROM 
  cscart_lock_keys 
WHERE 
  key_id = '0c922de3c12c8eb2b699fe4ed8fd4bae7ab6c48e61b0b60a9c43cd88588616a1' 
  AND token = 'ZQct0uGaLF99HdM6XpCYvjLODFqrk5lajCvBc46yVNw=' 
  AND expiry_at > UNIX_TIMESTAMP(NOW())

Query time 0.00025

JSON explain

{
  "query_block": {
    "select_id": 1,
    "message": "no matching row in const table"
  }
}