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SELECT 
  1 
FROM 
  cscart_lock_keys 
WHERE 
  key_id = '775835348c92d82a79e5359a0ea6daab089a3c9738666f46bad294cb70902752' 
  AND token = 'wgrd+BeVSmzxDLYzEbkjOkxuzkbXxdeR4VmgNoWx4G8=' 
  AND expiry_at > UNIX_TIMESTAMP(NOW())

Query time 0.00027

JSON explain

{
  "query_block": {
    "select_id": 1,
    "message": "no matching row in const table"
  }
}