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SELECT 
  1 
FROM 
  cscart_lock_keys 
WHERE 
  key_id = 'd5a1810281833b77589e45c6184f248fec01b010265a7716b8df5015b814d8a8' 
  AND token = '5mOWW/DtjdSeDOB9HbfkKpn7gyrOIKD7TijF5Uk6Q/g=' 
  AND expiry_at > UNIX_TIMESTAMP(NOW())

Query time 0.00028

JSON explain

{
  "query_block": {
    "select_id": 1,
    "message": "no matching row in const table"
  }
}