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SELECT 
  1 
FROM 
  cscart_lock_keys 
WHERE 
  key_id = 'b25c8b44108fc0e191add9cd29d080a7ce9ace60f654b515b7f19f5ed827b1ac' 
  AND token = 'VA3aKWgV2iRDBVsrp1vD7Fa7Q9V0bKdViZg0pZ8vWLU=' 
  AND expiry_at > UNIX_TIMESTAMP(NOW())

Query time 0.00024

JSON explain

{
  "query_block": {
    "select_id": 1,
    "message": "no matching row in const table"
  }
}