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SELECT 
  1 
FROM 
  cscart_lock_keys 
WHERE 
  key_id = '9f49e4e183487096b2e6f56cb83b639d86469d616ecdb6ba272c8a77a81e8b9a' 
  AND token = 'qwTKTuyF2Qy0gfXnUpSmXNlrAe4xLuDopwEpxd8Qa5A=' 
  AND expiry_at > UNIX_TIMESTAMP(NOW())

Query time 0.00034

JSON explain

{
  "query_block": {
    "select_id": 1,
    "message": "no matching row in const table"
  }
}