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SELECT 
  1 
FROM 
  cscart_lock_keys 
WHERE 
  key_id = '006c2b46b18bf586fe70db9e5fc46e64c20d10106b7a24e7f6f0677ec3f7b2fa' 
  AND token = '8YIQ1Mjm9ZHyRds9rwaKOOxMqYiq+TAiU/dqfpDkOjU=' 
  AND expiry_at > UNIX_TIMESTAMP(NOW())

Query time 0.00033

JSON explain

{
  "query_block": {
    "select_id": 1,
    "message": "no matching row in const table"
  }
}