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SELECT 
  1 
FROM 
  cscart_lock_keys 
WHERE 
  key_id = '72d0d5b9fecc37b64a58a6e3e6c1b83f34ef53bc76fe754b0afccd0c5aacff29' 
  AND token = 'ln3uea4pQdVgiSDxcUuzNXm+id4klbQN/4xEl/wY7lk=' 
  AND expiry_at > UNIX_TIMESTAMP(NOW())

Query time 0.00043

JSON explain

{
  "query_block": {
    "select_id": 1,
    "message": "no matching row in const table"
  }
}