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SELECT 
  1 
FROM 
  cscart_lock_keys 
WHERE 
  key_id = '7b2130f567e8ad8f4a973349f4ca6e1f4a10cb3e70f775098b49a6f1354e1acf' 
  AND token = 'YlRw/NUcx+ArEhsSVmypGx4T0jLuASFL0zZlty4d2zw=' 
  AND expiry_at > UNIX_TIMESTAMP(NOW())

Query time 0.00027

JSON explain

{
  "query_block": {
    "select_id": 1,
    "message": "no matching row in const table"
  }
}