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SELECT 
  1 
FROM 
  cscart_lock_keys 
WHERE 
  key_id = '04270babf9d7cf31e7c46f8c4eaed7a2be94fe986552f4795f314fde46a61258' 
  AND token = 'ue/G41WZgQq19RTpvw0oT6v4Ge049wkaKcuwHgL5Qiw=' 
  AND expiry_at > UNIX_TIMESTAMP(NOW())

Query time 0.00030

JSON explain

{
  "query_block": {
    "select_id": 1,
    "message": "no matching row in const table"
  }
}