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SELECT 
  1 
FROM 
  cscart_lock_keys 
WHERE 
  key_id = '650c7892963e30a5cb0accc58780490c3fb6b49ab514038668e7f4b857abf964' 
  AND token = '2K5K9MmigMvaPHmxdRmt1yGUAe9/jBbFhT+NUgkHncQ=' 
  AND expiry_at > UNIX_TIMESTAMP(NOW())

Query time 0.00033

JSON explain

{
  "query_block": {
    "select_id": 1,
    "message": "no matching row in const table"
  }
}