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SELECT 
  1 
FROM 
  cscart_lock_keys 
WHERE 
  key_id = '45a20dfec45498b1bd11d8ee7f5bcc02b177428aee1db524156d18cd7384f996' 
  AND token = 'YLj8n6UPKbsypOeOdu/qLaucQ69npjQ95xOg8tfOzd8=' 
  AND expiry_at > UNIX_TIMESTAMP(NOW())

Query time 0.00062

JSON explain

{
  "query_block": {
    "select_id": 1,
    "message": "no matching row in const table"
  }
}