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SELECT 
  1 
FROM 
  cscart_lock_keys 
WHERE 
  key_id = '85e43e460273bc41c4d7f02c4552bb82cceffbd2c29a387b6cf10b2977e1eac0' 
  AND token = 'hr0CkgkGAUKTx8K1JGQl1QSSKaUQR39PjgDjCdRLcTg=' 
  AND expiry_at > UNIX_TIMESTAMP(NOW())

Query time 0.00023

JSON explain

{
  "query_block": {
    "select_id": 1,
    "message": "no matching row in const table"
  }
}