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SELECT 
  1 
FROM 
  cscart_lock_keys 
WHERE 
  key_id = '470a453ab270de055566d65c8f0a39ad59e045eab7a6433b37d62f978b68af61' 
  AND token = 'DcYkEu8j5Sqx0SCwzMomc6Q8sxfzdIDt8iYZtSZwPFM=' 
  AND expiry_at > UNIX_TIMESTAMP(NOW())

Query time 0.00020

JSON explain

{
  "query_block": {
    "select_id": 1,
    "message": "no matching row in const table"
  }
}