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SELECT 
  1 
FROM 
  cscart_lock_keys 
WHERE 
  key_id = 'd93a7d404502a42304e9bdc16ec3910f61f3f397f4bb8da76359977616bbfedb' 
  AND token = 'ekYME+DYGpZEH1+FrUdAZd8xjWtHnmsGo3gAUaQdxuA=' 
  AND expiry_at > UNIX_TIMESTAMP(NOW())

Query time 0.00028

JSON explain

{
  "query_block": {
    "select_id": 1,
    "message": "no matching row in const table"
  }
}