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SELECT 
  1 
FROM 
  cscart_lock_keys 
WHERE 
  key_id = '38872662544085da278eaf592f88be8b5eb6d9a913d584099a0c2b4a985b1029' 
  AND token = 'A3jjHsLZLLjReN7GDoa3nJch2eKoF8F8mJZUmF226EA=' 
  AND expiry_at > UNIX_TIMESTAMP(NOW())

Query time 0.00035

JSON explain

{
  "query_block": {
    "select_id": 1,
    "message": "no matching row in const table"
  }
}