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SELECT 
  1 
FROM 
  cscart_lock_keys 
WHERE 
  key_id = '8e4cc69a0f14e3a07c5b3603944b58c08779bccd5001ef042a129528e925b2bb' 
  AND token = 'e5pTBkgTtaBNftY5e2anqN0EqD8ws95U2w51TsHl2aQ=' 
  AND expiry_at > UNIX_TIMESTAMP(NOW())

Query time 0.00036

JSON explain

{
  "query_block": {
    "select_id": 1,
    "message": "no matching row in const table"
  }
}