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SELECT 
  1 
FROM 
  cscart_lock_keys 
WHERE 
  key_id = 'c0a0bc75a4f7dad2e8c401c3f422dafea2dafe84ffbae0fc08cd105519444658' 
  AND token = 'tZl9XiXXW2dqpAC+E0tNJvQYSXyp/tGDA0aeIhrG1NQ=' 
  AND expiry_at > UNIX_TIMESTAMP(NOW())

Query time 0.00057

JSON explain

{
  "query_block": {
    "select_id": 1,
    "message": "no matching row in const table"
  }
}