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SELECT 
  1 
FROM 
  cscart_lock_keys 
WHERE 
  key_id = '035cc2b0096568fc075188b6f3e0a7c1eb29dd6ed2398262a61168da63a23385' 
  AND token = 'LOPMRWQ8v1K+O5QsmFN+GVAlEr9c8BKHO8FE6vmGR7M=' 
  AND expiry_at > UNIX_TIMESTAMP(NOW())

Query time 0.00033

JSON explain

{
  "query_block": {
    "select_id": 1,
    "message": "no matching row in const table"
  }
}