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SELECT 
  1 
FROM 
  cscart_lock_keys 
WHERE 
  key_id = '2e225426b66f576854cee9cc66e10b0c56e766138cd7b437304cc255ff75d1e6' 
  AND token = 'CPfDt4nSxzbjOirjVWcY7cgNahxNmW+7bKCHDOMYyws=' 
  AND expiry_at > UNIX_TIMESTAMP(NOW())

Query time 0.00036

JSON explain

{
  "query_block": {
    "select_id": 1,
    "message": "no matching row in const table"
  }
}