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SELECT 
  1 
FROM 
  cscart_lock_keys 
WHERE 
  key_id = 'cfcc0bf5026e32fb3ce11dad9184fa791aefa7652394aac3623ed68f02a14ada' 
  AND token = '5d3AkmbO+vfFDmKk9u1DGKK3m4SFDozhOGal/bYXgeQ=' 
  AND expiry_at > UNIX_TIMESTAMP(NOW())

Query time 0.00024

JSON explain

{
  "query_block": {
    "select_id": 1,
    "message": "no matching row in const table"
  }
}