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SELECT 
  1 
FROM 
  cscart_lock_keys 
WHERE 
  key_id = '2015cce1787626e632b298e51975c344d21b868998c1e0024b891b7d73a4ace4' 
  AND token = 'EagZsf6NaWUMFSXXLe+RzOcGAzao0JrIGa/O+F0XHCg=' 
  AND expiry_at > UNIX_TIMESTAMP(NOW())

Query time 0.00046

JSON explain

{
  "query_block": {
    "select_id": 1,
    "message": "no matching row in const table"
  }
}