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SELECT 
  1 
FROM 
  cscart_lock_keys 
WHERE 
  key_id = 'b380dafde0ec2ae38f0b4e234e62d917e50bb5deef9003c23a1525270f0fa617' 
  AND token = '5KxG5PR/1LE5q4UEBIlfP1dA0uYg5gR8FJ2BcH06qlQ=' 
  AND expiry_at > UNIX_TIMESTAMP(NOW())

Query time 0.00048

JSON explain

{
  "query_block": {
    "select_id": 1,
    "message": "no matching row in const table"
  }
}