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SELECT 
  1 
FROM 
  cscart_lock_keys 
WHERE 
  key_id = 'c6d378bd792bf9973ab107b8a475c6d2b87632860f35b9cec7b5adb854b1a3d7' 
  AND token = 'Z8G4OU1Au2sCsEyoGozDDO9nW63ZnlfXcJKwVAhZnMg=' 
  AND expiry_at > UNIX_TIMESTAMP(NOW())

Query time 0.00028

JSON explain

{
  "query_block": {
    "select_id": 1,
    "message": "no matching row in const table"
  }
}