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SELECT 
  1 
FROM 
  cscart_lock_keys 
WHERE 
  key_id = '8df80d87f2c08a1a329c1af8d87f8f5798a7cc1c556214a2b2377c78d6c56f24' 
  AND token = 'zwt+8t4Hlz0M1RrKKbdeBzTAO7HKNDL/J11Ssl2ZOu8=' 
  AND expiry_at > UNIX_TIMESTAMP(NOW())

Query time 0.00027

JSON explain

{
  "query_block": {
    "select_id": 1,
    "message": "no matching row in const table"
  }
}