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SELECT 
  1 
FROM 
  cscart_lock_keys 
WHERE 
  key_id = 'e4b202b8a835932c727e2fd24c7315267b86933d34c475fbd0ca9a018451617f' 
  AND token = 'FsACxsirIO5hfF0msFs+yTCw+1L5/ZYlSThJgA5e4ck=' 
  AND expiry_at > UNIX_TIMESTAMP(NOW())

Query time 0.00026

JSON explain

{
  "query_block": {
    "select_id": 1,
    "message": "no matching row in const table"
  }
}